This PGS Detection Kit is used for the qualitative detection of embryonic cells obtained by intracytoplasmic sperm injection (ICSI), including whole-genome amplification products of blastomere cells (Day 3) or blastocyst trophoblast cells (Day 5). By analyzing the DNA sequence information in the single-cell whole genome amplification product, the difference in the number of chromosomes in the test sample is obtained, and 23 chromosomes are detected at one time to evaluate whether the embryo chromosome has abnormal number and copy number variation. According to the results of the test, embryos without chromosomal abnormalities (aneuploidy and copy number variation) are selected for transplantation, and the success rate of embryo transfer is improved. The test results are not the only criteria for embryo implantation. They are only for clinically assisted diagnosis. For implanted embryos, the prenatal diagnostic gold standard (karyotype analysis) is confirmed after successful pregnancy.
The test kit is suitable for pre-implantation testing of In Vitro cultures embryos for couples who are expected to be IVF. The intended use is not limited to elderly, couples with recurrent miscarriage or repeated implant failure were tested for 24 chromosome aneuploidy before embryo implantation.