Human beta-amyloid 1-40 (Aβ40) detection kit & Human beta-amyloid 1-42 (Aβ42) detection kit (Digital Immunochip Method)

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Harnessing cutting-edge Digital Immunochip technology, these kits enable the precise quantification of Beta-Amyloid (1-40 and 1-42) at the femtogram level. A non-invasive solution designed to assess cortical amyloid burden and cognitive decline risk through the Aβ42/40 ratio—a key metric highly correlated with amyloid PET positivity.

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Description

Amyloid plaques are a hallmark pathological feature of Alzheimer’s Disease (AD). The Human β-Amyloid 1-42 and 1-40 Detection Kits by iomics Biosciences provide an essential quantitative tool for clinical aid in AD diagnosis, screening, and staging.

Key Features:

  • Ultra-Sensitivity (1,000x over ELISA): Quantify trace proteins at femtogram-per-microliter levels, enabling the detection of pathological changes years before clinical onset.
  • The Diagnostic Power of Aβ42/40 Ratio: Plasma Aβ42/40 ratios are strongly associated with higher cortical amyloid burden and faster cognitive decline, providing a reliable alternative to invasive CSF detection.
  • Intelligent Digital Detection: Combines double-antibody sandwich immunoassays with AI-based image recognition to capture and count individual molecule signals within femtoliter-sized microwells.
  • Optimized Laboratory Efficiency: Delivers results in 20-30 minutes with a minimal 25 μL loading volume, ensuring rapid turnaround for high-demand clinical environments.
  • Early Detection Capabilities: Identifies neurodegenerative biomarkers detectable up to 10-20 years before symptoms manifest, reshaping both research and clinical approaches to AD.

Technical Specifications:

  • Packaging: 48 tests/kit or 96 tests/kit.
  • Sample Compatibility: Human Plasma.
  • System Integration: Fully optimized for the Inspirer DX Analyzer.