Human neurofilament light chain protein (NfL) detection kit (Digital Immunochip Method)

Harnessing revolutionary Digital Immunochip technology, this kit delivers 1,000x greater sensitivity than traditional assays for quantifying Neurofilament Light chain (NfL) in human plasma. A non-invasive diagnostic tool essential for monitoring neurodegeneration, brain atrophy, and clinical progression in Alzheimer's (AD), Multiple Sclerosis (MS), and Traumatic Brain Injury (TBI).

Description

Neurofilament light chain (NfL) is a major component of the axonal cytoskeleton, providing structural stability and influencing conduction velocity. As a reliable indicator of axonal injury, elevated plasma NfL levels are directly associated with cognitive decline and brain atrophy, making it a “universal” biomarker for neurodegenerative disorders.

Key Features:

  • Femtogram-Level Sensitivity: Utilizing single-molecule digital detection, the system captures trace proteins at ultra-low concentrations that conventional ELISA cannot reach, enabling the earliest possible detection of neuronal damage.
  • Broad Clinical Utility: Plasma NfL levels serve as a powerful tool for differentiating disease stages and monitoring therapeutic efficacy across a spectrum of conditions, including AD, MS, ALS, and traumatic brain injury.
  • Non-Invasive Diagnostic Precision: Optimized for human plasma, this kit provides a practical, patient-friendly alternative to invasive CSF collection, allowing for frequent and safe monitoring of disease progression.
  • Rapid & Efficient Workflow: Designed for the Inspirer DX Analyzer, it delivers high-accuracy results in just 20-30 minutes with a minimal 25 μL sample volume.
  • Advanced AI Integration: Employs a double-antibody sandwich assay combined with AI-based image recognition to ensure absolute quantification of target molecules.

Technical Specifications:

  • Packaging: 48 tests/box or 96 tests/box.
  • Sample Type: Human Plasma.
  • System Compatibility: Fully optimized for the Inspirer DX Analyzer.