Human glial fibrillary acidic protein (GFAP) detection kit (Digital Immunochip Method)

Delivering 1,000x greater sensitivity than conventional assays, the iomics GFAP Detection Kit (Digital Immunochip Method) enables precise quantification of astrocyte activation directly from blood samples. It provides a superior, non-invasive diagnostic solution for differentiating Alzheimer’s Disease (AD) from other cognitive disorders and monitoring pathological progression through amyloid burden and neuronal loss.

Description

In the pathogenesis of Alzheimer’s Disease, GFAP serves as a critical indicator of astrocyte activation and reactive proliferation, appearing early in the disease continuum. Our GFAP Detection Kit, optimized for the Inspirer DX Analyzer, provides femtogram-level sensitivity, allowing clinicians to identify pathological changes 10–20 years before clinical symptoms manifest.

Key Features:

  • Ultra-Sensitive Digital Detection: Utilizes single-molecule immunoassay technology to achieve a detection limit of 2.5 fg/mL, enabling the detection of plasma GFAP elevations that correlate strongly with Aβ plaque severity and neurofibrillary tangles.
  • Proven Diagnostic Accuracy: Clinical evidence highlights significant GFAP upregulation in the cerebral cortex and hippocampus of AD patients; combining GFAP with Aβ42 and Tau biomarkers offers robust support for accurate AD diagnosis.
  • Intelligent Digital Immunochip Workflow: Employs high-density microfluidic biochips and AI-based pattern recognition to capture and count individual fluorescent signals, ensuring unmatched data integrity.
  • Non-Invasive Efficiency: Delivers high-precision results in just 20–30 minutes with a minimal 25 μL plasma volume, providing a practical alternative to invasive CSF collection or expensive PET imaging.
  • Versatile Clinical Utility: An essential tool for auxiliary AD diagnosis, patient stratification, therapeutic efficacy monitoring in drug R&D, and neurological research.

Technical Specifications:

  • Product Name: Human Glial Fibrillary Acidic Protein (GFAP) detection kit (Digital Immunoassay Chip Method).
  • Packaging: 48 tests/box or 96 tests/box.
  • Sample Compatibility: Human Plasma.
  • System Integration: Fully optimized for the Inspirer DX Analyzer.