MassARRAY Analyzer

Description

The system is a chemical analysis platform designed to determine the concentration and identity of chemical substances within a sample by measuring the mass-to-charge ratio and the abundance of gas-phase ions.

Principles of Operation

The system utilizes mass spectrometry to analyze charged molecules as they move through an electric field. The sample is ionized into various charged molecules, which are then separated based on their specific m/z values. Mass spectral data is automatically recorded and utilized for protein identification through bioinformatics tools.

General Operation and Architecture

The workflow of the MassARRAY Analyzer consists of three primary stages:

  1. Ionization: The sample is converted into ions in various charge states.
  2. Separation: Sample ions are separated based on their m/z differences.
  3. Detection & Analysis: The mass spectra of the separated ions are recorded.

Integrated bioinformatics software enables database searching and comprehensive result analysis. The mass spectrometer does not measure mass (m) directly; instead, it measures the mass-to-charge ratio (m/z).

Specifications

  • Dimensions: 37W x 43H x 27D in (104W x 110H x 68D cm)
  • Capacity: 2 x Microtiter plates (96-well), 2 x SpectroCHIP CPM 96 Arrays
  • Processing Time: Approximately 90 minutes per 96-well plate

Biological Applications

The system is applicable across all clinical diagnostic fields, including: NIPT (Non-Invasive Prenatal Testing), Oncology (Cancer research and diagnostics), Pharmacogenomics (Medication safety and efficacy), Microbiology (Bacterial and viral detection)